Progress in the Latest Technology of Biological Toxicity Test

In recent years, the public has become increasingly concerned about the toxicity of the compounds in the environment, and the toxic pollution has become a worldwide problem. In order to solve these problems, it need to quantitatively evaluate the quality of the water from the perspective of toxicity test. In particular, after the \”911\” incident, people paid more attention to water quality and safety, and all kinds of accidents associated with water quality whether which were made by man or nature. Toxicity testing is the key to solve the problem. It can be said that in addition to the soil and air monitoring, water quality analysis has become a more important task.

The detection method of aquatic organisms such as plankton, algae, fish and other aquatic organisms has become one of the necessary means to evaluate the environmental pollution. However, due to its long detection time and high detection cost, it is no longer suitable for routine inspection.

In recent years, some rapid, simple and economical modern detection methods have been developed, such as the detection method of luminescent bacteria and the method of chemiluminescence detection. Luminescent bacteria is one of the most commonly used methods for the evaluation of acute toxicity, while the chemiluminescence method is a new technique for evaluating the toxicity of the chemical, and the chemical reaction is a method to determine the content of the material in the reaction. As an effective analytical technique, chemiluminescence method has been widely used in pharmaceutical analysis, food safety, environmental science, life science and other fields.(Reference: Advanced Physiological Pharmaceutical Model from PBPK Records)

It is based on the method of a series of advantages, a company successfully developed a water quality and biological toxicity test instrument – portable water quality analyzer. The instrument can make an assessment of the water source and drinking water pollution caused by the sudden or artificial damage in the first time. The instrument was originally developed for the military biological toxicity detection technology, and now as a fast, portable water quality and safety testing tool in the world, it has been more and more widely used.

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The strategy of toxicity testing will be based on the traditional model of the whole animal toxicity test system and human cells, cell lines or cell components in vitro test system. Future toxicity testing and risk assessment strategies should be based on the \”toxic pathway\” by studying and analyzing the changes of the cell or cell components, and exploring the effects of chemicals on the biological process. This scientific vision and strategic philosophy is intended to study how foreign chemicals can damage the molecular pathways and identify the initiating critical events that lead to harmful health effects and their cascade reactions. \”Molecular pathways\” can be understood as genes, proteins and small molecules that interact to maintain cell function \”. New ideas, new technologies and new strategies for toxicity testing will undoubtedly boost the change of health risk assessment methods for chemical substances, and will further improve the risk management based on science.

Creative Animodel is an experienced bioscience CRO. We would like to help you accelerate the process through our preclinical services including PD, PK, toxicology services and the establishment of tumor-bearing animal models.Feel free to contact us at http://www.creative-animodel.com/. References: toxicity test Advanced Physiological Pharmaceutical Model from PBPK Records

Creative Animodel is an experienced bioscience CRO. We would like to help you accelerate the process through our preclinical services including PD, PK, toxicology services and the establishment of tumor-bearing animal models.Feel free to contact us at http://www.creative-animodel.com/. References: toxicity test:http://www.creative-animodel.com/Toxicology/Genetic-and-Molecular-Toxicology-Assays.html Advanced Physiological Pharmaceutical Model from PBPK Records:http://www.adme-pharmacodynamics.com/advanced-physiological-pharmaceutical-model-from-pbpk-records/

Author Bio: Creative Animodel is an experienced bioscience CRO. We would like to help you accelerate the process through our preclinical services including PD, PK, toxicology services and the establishment of tumor-bearing animal models.Feel free to contact us at http://www.creative-animodel.com/. References: toxicity test Advanced Physiological Pharmaceutical Model from PBPK Records

Category: Medical Business
Keywords: toxicity test, water quality analyzer

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